FRAGILITY IN THE 14Q21Q TRANSLOCATION REGION

Fragility in the 14q21q translocation region

Aphidicolin (APC)-induced chromosomal breakage was analyzed for women representing three generations of a single family and Jandy LRZ Parts carrying a Robertsonian translocation rob(14q21q).Fluorescence in situ hybridization (FISH) analysis confirmed the dicentric constitution of the derived chromosome and indicated the absence of beta-satellite si

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